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1.
Med Oral Patol Oral Cir Bucal ; 23(4): e454-e462, 2018 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-29924769

RESUMO

BACKGROUND: To assess whether the techniques of percutaneous needle electrolysis (PNE) and deep dry needling (DDN) used on trigger points (TrP) of lateral pterygoid muscle (LPM) can significantly reduce pain and improve function in patients with myofascial pain syndrome (MPS) compared to a control group treated with a sham needling procedure (SNP). MATERIAL AND METHODS: Sixty patients diagnosed with MPS in the LPM were selected and randomly assigned to one of three groups. The PNE group received electrolysis to the LPM via transcutaneous puncture. The DDN group received a deep puncture to the TrP without the introduction of any substance. In the SNP group, pressure was applied to the skin without penetration. Procedures were performed once per week for 3 consecutive weeks. Clinical evaluation was performed before treatment, and on days 28, 42 and 70 after treatment. RESULTS: Statistically significant differences (p <0.01) were measured for the PNE and DDN groups with respect to pain reduction at rest, during chewing, and for maximum interincisal opening (MIO). Values for the PNE group showed significantly earlier improvement. Differences for PNE and DDN groups with respect to SNP group were significant (p <0.05) up to day 70. Evaluation of efficacy as reported by the patient and observer was better for PNE and DDN groups. No adverse events were observed for either of the techniques. CONCLUSIONS: PNE and DDN of the LPM showed greater pain reduction efficacy and improved MIO compared to SNP. Improvement was noted earlier in the PNE group than in the DDN group.


Assuntos
Terapia por Acupuntura , Terapia por Estimulação Elétrica , Síndromes da Dor Miofascial/terapia , Terapia por Acupuntura/métodos , Adolescente , Adulto , Idoso , Método Duplo-Cego , Terapia por Estimulação Elétrica/instrumentação , Eletrólise , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Agulhas , Músculos Pterigoides , Espanha , Pontos-Gatilho , Adulto Jovem
2.
Med Chem ; 5(1): 44-9, 2009 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-19149649

RESUMO

We investigated the effect of magnetic field stimulation (MS) on oxidative damage and skeletal muscle injury prompted by mepivacaine injection in the anterior tibial muscle of Wistar rats. The effects of mepivacaine and MS on oxidative stress were evaluated by lipid peroxidation, GSH levels and catalase activity. Muscle regeneration was analyzed by haematoxylin-eosin stained, NADH-TR histochemical reaction, desmin immunostaining as well as by morphometric parameters such as fibers density and fiber area were evaluated. Our data revealed that mepivacaine induced oxidative stress, that MS prevents the harmful effects induced by mepivacaine and that it facilitates the regeneration process of skeletal muscle. In conclusion, the results show the ability of MS to modify skeletal muscle response to mepivacaine.


Assuntos
Magnetoterapia , Mepivacaína/farmacologia , Músculo Esquelético/efeitos dos fármacos , Músculo Esquelético/fisiologia , Estresse Oxidativo/efeitos dos fármacos , Estresse Oxidativo/fisiologia , Regeneração/efeitos dos fármacos , Animais , Radicais Livres/metabolismo , Injeções Intramusculares , Masculino , Mepivacaína/administração & dosagem , Nitritos/metabolismo , Ratos , Ratos Wistar
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